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Brain Pain: How Central Sensitization Creates Chronic Pain

Updated: Feb 14

Pain, especially chronic pain, is complex consisting of environmental, social, physiological, psychological and energetic components. All of these elements are juggled by our nervous systems, emphasized and de-emphasized according to inner resource availability and unconscious priority, in an effort to prevent [further] harm. However, sometimes the body can be overzealous in its guardian duties. One example of this overprotective nature is called central sensitization.

areas of the brain involved in central sensitization, a key contributor to chronic pain

Central sensitization is defined as changes in the brain and spinal cord that create a heightened reactivity to noxious or potentially noxious stimuli. In other words, your brain turns its pain perception up to eleven (because eleven is more) making painful sensations feel more painful than usual and, in extreme cases, perceiving innocuous touch as threatening. This mechanism is thought to contribute largely to chronic pain. Because every incident of pain puts your nervous system on higher alert requiring increasingly smaller sensations to set off pain, a person with central sensitization will feel more pain with less prompting over time.

Breaking this cycle depends on how advanced the condition is, though evidence that suggests central sensitization is always reversible. Doing so involves demonstrating to the central nervous system that the danger has passed and working the pain perception dial back down to a reasonable level. The process will go much more smoothly in the safe environment created by a knowledgeable professional such as a physical therapist, occupational therapist, or massage therapist.

Further reading on this subject can be found here:

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